Hi, I'm Constantin.
I'm a scientist, engineer, and founder, though those labels matter less to me than what I'm actually trying to do, which is live long enough to see everything worth seeing. Eighty years isn't enough. There's too much universe, too much to build, too many people still to meet.
Somewhere along my way I realized (dying) aging is the bottleneck, the single biggest unsolved problem in life science and I decided to make it my life's work. I'm especially drawn to information-theoretic and stochastic theories of aging, and the question of whether we can actually reverse them. If yes, I will.
A few things about me
- I sold my first company at 17, and I've spent most of the last five years in labs of one kind or another.
- I'm finishing my MD this June.
- Right now I split my time between learning as much math and biology as I can hold in my head, incubating companies out of what might be Central Europe's most notorious hacker house, and helping build a global society of people obsessed with humanity's biggest open questions.
- Beyond aging, I get lost in AI, math, physics, neuroscience, biotech, philosophy, and engineering.
If any of this resonates — or you just want to argue about whether we can actually solve death — I'd love to hear from you.
Selected proof of work
Currently
What I'm building right now
Reversing aging at its root
Information-theoretic and stochastic theories of aging — and the question of whether the damage can be reversed, not just slowed. Incoming at the Gladyshev Lab (HMS / Brigham).
The full timeline → CommunityThe Residency Vienna
A 500 m² hacker house. Companies that came through it hold a combined ~€100M valuation; two were pulled into HF0, one of the most selective incubators on earth.
Visit The Residency → NetworkTelos Circle
Wiring European deep-tech to the US frontier — curated dinners, founder residencies, and a growing transatlantic network of people obsessed with humanity's biggest open questions.
Visit Telos Circle →Open tabs
What I'm thinking about
The questions currently eating most of my attention. If you have a strong take on any of them, that's a great reason to write me.
- 01 Is the information lost in aging recoverable — or only slowable?
- 02 What would an actually trustworthy clock of biological age look like?
- 03 Where does AI genuinely shorten the loop between hypothesis and hit in biology?
- 04 Stochastic damage vs. information-theoretic decay — which one breaks first?
- 05 How do you build a transatlantic scene dense enough that talent compounds?
Writing
Thinking out loud
Essays at the intersection of longevity, AI, and the philosophy of biology — where most of my real thinking happens.
Aging as the dissolution of self-referential chromatin loops
A sketch toward a perspective paper. What if the four-pillar framework of aging, Hofstadter's strange loops, autopoiesis, and the Buddhist view of anatta are all pointing at the same thing — and aging is what happens when the self-reference runs down?
Read the essay →Let's argue about whether we can solve death.
Collaborator, co-author, or co-conspirator — in longevity, AI for medicine, biotech founding, or the philosophy of biology. If any of this resonates, I want to hear from you.